For the first time a new test has been developed that tailors the timing of IVF treatment to a woman’s individual cycle. The scientists behind the technique believe that IVF frequently fails because the embryo is transferred at the wrong time, missing a crucial fertility window. The new test pinpoints a woman’s optimum time for treatment and in pilot studies the approach significantly boosted success rates.
There are more than 60,000 IVF cycles in Britain each year, but just 24% of these treatments lead to live births. Clinics currently check the visual appearance of the womb lining using ultrasound, giving a general indication of health. In the pilot study, the test was given to 85 women who had each experienced on average five rounds of IVF that had failed at the implantation stage. When the gene analysis was used as a guide, 33% of those treated had a successful implantation simply by just changing the day.
Nick Macklon, professor of obstetrics and gynaecology at the University of Southampton, believes that issues linked to the womb lining explain around two-thirds of cases of recurrent implantation failure, with around one-third of cases being due to embryo abnormalities. He asserts that these tests could significantly improve success rates.